- Nebula's appearance in the movie seems to be based more on her second incarnation from the comics.
- Nebula shows complete loyalty to Thanos most of the time, but also states that she would gladly destroy a thousand worlds if it meant Thanos would die. This is possibly out of fear towards him, but may also be out of hatred, due to Thanos constantly undermining her in favor of Gamora.
- In Guardians of the Galaxy Prelude, Nebula loses her entire left arm and has it replaced by cybernetics; however, in Guardians of the Galaxy, her left hand appears to be made of flesh.
- She is right-handed.